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Unlocking the Secrets of Cell Cycle Gene Expression

Understanding how genes behave during the cell cycle is fundamental to molecular biology, cancer research, and drug discovery. Using the powerful model organism Schizosaccharomyces pombe (fission yeast), researchers have mapped the precise timing and coordination of gene expression that drives cell division.Understanding how genes behave during the cell cycle is fundamental to molecular biology, cancer research, and drug discovery. Using the powerful model organism Schizosaccharomyces pombe (fission yeast), researchers have mapped the precise timing and coordination of gene expression that drives cell division.




Why It Matters ?

Cell cycle regulation is not only key to basic science but also central to:


🧪 Cancer research – understanding uncontrolled cell division


🧬 Biomarker discovery – identifying cycle-phase-specific genes


⚙️ Synthetic biology – programming gene expression timing



We develop the ideal
customized solution for your needs

Microarray-Based Expression Data

Leverage large-scale expression profiles from synchronized cell cycle experiments.

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 Cell Cycle-Phased Gene Clusters

  • Gain insights into genes activated during specific stages:
  • Early/mid G2 phase – linked to ribosome biogenesis
  • G2/M transition – involving mitosis, DNA replication, and cytokinesis

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Cross-Species Conservation

Compare regulatory mechanisms and promoter structures conserved between S. pombe and S. cerevisiae.

Uncover the Genetic Clockwork Behind Cell Division

Schizosaccharomyces pombe (S. pombe), also known as fission yeast, is a powerful model organism widely used to study the cell cycle, gene regulation, and chromosome biology. Its relatively simple genome and conserved molecular mechanisms make it a preferred system for uncovering the genetic principles that govern eukaryotic cell division.



 Short generation time (~2-3 hours)

Well-characterized genome (~14 million base pairs)

High conservation of cell cycle genes with humans



Robust for microarray, RNA-seq, and CRISPR-based studies

Easily synchronized for cell cycle phase analysis


Discover More

  • Analyze over 750 highly regulated cell cycle genes
  • Explore functional gene groups by expression phase
  • Visualize transcription waves and promoter motif patterns
  • Download curated, normalized data for custom analysis
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